FabSwingers.com forum: Antibody dependent enhancement / pathogenic priming

By *tarsky OP Man
over a year ago

South Devon

What’s everyone’s thoughts on ADE / PP? Most fabbers appear to have already had, or are keen to get, their COVID vaccine, so presumably don’t anticipate it’ll be much of a problem...?

By *inky_couple2020Couple
over a year ago

North West

Here's a good article on the topic. ADE occurs in natural diseases so is a risk with being infected by certain diseases anyway and we have zero evidence that the Covid vaccines will induce this. They have been designed specifically to avoid this (by using the spike protein in its pre-fusion conformation rather than the form that exists post-binding to human cells).

Title of article: Antibody-Dependent Enhancement

By Derek Lowe 18 December, 2020

Website: Science Translational Medicine

By *olly_chromaticTV/TS
over a year ago

Stockport

"Here's a good article on the topic. ADE occurs in natural diseases so is a risk with being infected by certain diseases anyway and we have zero evidence that the Covid vaccines will induce this. They have been designed specifically to avoid this (by using the spike protein in its pre-fusion conformation rather than the form that exists post-binding to human cells).

Title of article: Antibody-Dependent Enhancement

By Derek Lowe 18 December, 2020

Website: Science Translational Medicine"

Excellent article!