FabSwingers.com mobile

Already registered?
Login here

Back to forum list
Back to Virus

Vaccines via pillor nasal spray

Jump to newest
 

By *ophieslut OP   TV/TS
over a year ago

Central

Would the form of the vaccine influence your take-up of it? The Oxford team are looking at vaccine tablet or nasal spray versions.

Reply privatelyReply in forumReply +quote
 

By (user no longer on site)
over a year ago

Yes I would.

Reply privatelyReply in forumReply +quote
 

By *luttyLaylaWoman
over a year ago

North West


"Would the form of the vaccine influence your take-up of it? The Oxford team are looking at vaccine tablet or nasal spray versions. "

Not for healthy adults with no other issues. No one likes a needle but you do it anyway. I think this should just be the quickest way to create theme

For people with fears, disabilities and children- definitely

Reply privatelyReply in forumReply +quote
 

By *naswingdressWoman
over a year ago

Manchester (she/her)

I'm phobic, but no.

I heard a suggestion - just a hint of an idea, mind (sort of, this is possibly the case) - that nasal vaccines might be more effective than needles. But unless or until that's proven so and is the type on the market, I'll take what I'm given.

Reply privatelyReply in forumReply +quote
 

By *ophieslut OP   TV/TS
over a year ago

Central


"I'm phobic, but no.

I heard a suggestion - just a hint of an idea, mind (sort of, this is possibly the case) - that nasal vaccines might be more effective than needles. But unless or until that's proven so and is the type on the market, I'll take what I'm given."

There's the concept that a nasal spray could deliver the vaccine to the point of likely first entry in to the body, where infection can build - the vaccine could do the reverse, potentially building strong immunity starting at the same place. It's over simplistic I'm sure, as the whole body can create a substantial, comprehensive immune response.

I can see that our global shortage of supplies like syringes could be overcome via alternative delivery vehicles and styles. And also that some people could be more inclined to take a tablet, rather than get a needle. It may be quicker to deliver via these alternatives, potentially cheaper and overcoming stringent storage requirements for liquids.

The biggest ease, if it was a new pandemic, could be the very high volume delivery to more people, enabling a more rapid reduction in deaths/infections and potentially reaching herd immunity. For poorer countries, with minimal health care facilities and networks, tablets may be a more appropriate solution. That said, vaccination under supervision does help to ensure that people get the treatments that they need.

Reply privatelyReply in forumReply +quote
 

By *naswingdressWoman
over a year ago

Manchester (she/her)


"I'm phobic, but no.

I heard a suggestion - just a hint of an idea, mind (sort of, this is possibly the case) - that nasal vaccines might be more effective than needles. But unless or until that's proven so and is the type on the market, I'll take what I'm given.

There's the concept that a nasal spray could deliver the vaccine to the point of likely first entry in to the body, where infection can build - the vaccine could do the reverse, potentially building strong immunity starting at the same place. It's over simplistic I'm sure, as the whole body can create a substantial, comprehensive immune response.

I can see that our global shortage of supplies like syringes could be overcome via alternative delivery vehicles and styles. And also that some people could be more inclined to take a tablet, rather than get a needle. It may be quicker to deliver via these alternatives, potentially cheaper and overcoming stringent storage requirements for liquids.

The biggest ease, if it was a new pandemic, could be the very high volume delivery to more people, enabling a more rapid reduction in deaths/infections and potentially reaching herd immunity. For poorer countries, with minimal health care facilities and networks, tablets may be a more appropriate solution. That said, vaccination under supervision does help to ensure that people get the treatments that they need. "

It certainly has a number of plus points. I hope it's investigated, for Covid and otherwise.

Needles terrify me but I'll suck it up.

Reply privatelyReply in forumReply +quote
 

By (user no longer on site)
over a year ago

Birmingham university have already developed one. It could be in the shops for summer. For some reason no one is talking about it!

Reply privatelyReply in forumReply +quote
 

By *tockport 69Couple
over a year ago

Stockport

hope it come soon as I can not have the jabs .

Reply privatelyReply in forumReply +quote
 

By *naswingdressWoman
over a year ago

Manchester (she/her)

My coping mechanism for needles involves me biting myself. That'll be... interesting with masks

Reply privatelyReply in forumReply +quote
 

By *icecouple561Couple
Forum Mod

over a year ago

East Sussex

Our son is genuinely needle phobic. I'm hoping that something like this becomes available for him and people like him.

Reply privatelyReply in forumReply +quote
 

By *mmabluTV/TS
over a year ago

upton wirral

I hate needles but cannot undersand why it would make people more likely to have vaccine as long as the results are the same that is what matters surely

Reply privatelyReply in forumReply +quote
 

By *naswingdressWoman
over a year ago

Manchester (she/her)


"I hate needles but cannot undersand why it would make people more likely to have vaccine as long as the results are the same that is what matters surely"

Depends on the degree of the needle phobia.

As a child I had to learn not to instinctively attack the person with the needle. If I hadn't settled down (I'm still scared) and I didn't think getting vaccinated was personally beneficial, then a spray might tip the balance for me. (I'll get the jab as soon as I'm offered)

Reply privatelyReply in forumReply +quote
 

By *icecouple561Couple
Forum Mod

over a year ago

East Sussex


"I hate needles but cannot undersand why it would make people more likely to have vaccine as long as the results are the same that is what matters surely"

There's a big difference between hating needles and being genuinely phobic.

Our son has refused treatment rather than have an injection.

Reply privatelyReply in forumReply +quote
 

By *naswingdressWoman
over a year ago

Manchester (she/her)


"I hate needles but cannot undersand why it would make people more likely to have vaccine as long as the results are the same that is what matters surely

There's a big difference between hating needles and being genuinely phobic.

Our son has refused treatment rather than have an injection. "

I'm probably low level phobic. "Swing you must not hit the nurse. Swing you must not hit the nurse". It's a mantra. It took years of training

Reply privatelyReply in forumReply +quote
 

By *icecouple561Couple
Forum Mod

over a year ago

East Sussex


"I hate needles but cannot undersand why it would make people more likely to have vaccine as long as the results are the same that is what matters surely

There's a big difference between hating needles and being genuinely phobic.

Our son has refused treatment rather than have an injection.

I'm probably low level phobic. "Swing you must not hit the nurse. Swing you must not hit the nurse". It's a mantra. It took years of training "

Our son passes out. At that point consent can't be given. I know why he's phobic. He was very ill when he was 6 weeks old and had to have blood tests, it was obviously terrifying for him

Reply privatelyReply in forumReply +quote
 

By *naswingdressWoman
over a year ago

Manchester (she/her)


"I hate needles but cannot undersand why it would make people more likely to have vaccine as long as the results are the same that is what matters surely

There's a big difference between hating needles and being genuinely phobic.

Our son has refused treatment rather than have an injection.

I'm probably low level phobic. "Swing you must not hit the nurse. Swing you must not hit the nurse". It's a mantra. It took years of training

Our son passes out. At that point consent can't be given. I know why he's phobic. He was very ill when he was 6 weeks old and had to have blood tests, it was obviously terrifying for him"

I get it. Well, not literally, but I empathise. I get queasy and faint, and struggle to resist lashing out. I usually bite myself. (But obviously given my thyroid condition, blood tests are part of my life)

I'd much prefer a nasal vaccine, but I *can* and do handle needles. It'd be better to give less fear/phobia inducing treatment where possible.

Reply privatelyReply in forumReply +quote
 

By *icecouple561Couple
Forum Mod

over a year ago

East Sussex


"I hate needles but cannot undersand why it would make people more likely to have vaccine as long as the results are the same that is what matters surely

There's a big difference between hating needles and being genuinely phobic.

Our son has refused treatment rather than have an injection.

I'm probably low level phobic. "Swing you must not hit the nurse. Swing you must not hit the nurse". It's a mantra. It took years of training

Our son passes out. At that point consent can't be given. I know why he's phobic. He was very ill when he was 6 weeks old and had to have blood tests, it was obviously terrifying for him

I get it. Well, not literally, but I empathise. I get queasy and faint, and struggle to resist lashing out. I usually bite myself. (But obviously given my thyroid condition, blood tests are part of my life)

I'd much prefer a nasal vaccine, but I *can* and do handle needles. It'd be better to give less fear/phobia inducing treatment where possible."

Yes it would if it were possible.

We're looking in to ways to help him overcome his phobia.

Reply privatelyReply in forumReply +quote
 

By (user no longer on site)
over a year ago

There’s quite a few alternative technologies out there, which have come and gone, like transdermal injections. For one reason or another they haven’t taken off.

Reply privatelyReply in forumReply +quote
 

By *inky_couple2020Couple
over a year ago

North West

Nasal spray vaccines already exist. The children's flu vaccine is in this form. It's a live virus vaccine so very different to the Covid vaccines. The issue would be establishing a mechanism to get the mRNA or viral vector to be taken up in sufficient quantities by the nasal epithelial cells, to provoke a sufficient immune response. The fact is that jabbing into a large muscle gets the vaccine material into the bloodstream rapidly and thus rapidly to cells. This efficiency cannot be mirrored by a spray up the nose, so formulations and all sorts of other things need to change.

Reply privatelyReply in forumReply +quote
 

By *ophieslut OP   TV/TS
over a year ago

Central


"Birmingham university have already developed one. It could be in the shops for summer. For some reason no one is talking about it! "

The Birmingham uni development is potentially great, as an immediate protective agent. It's not 1 of the vaccines that will get the body to produce immunity, as far as I can recall, like the Pfizer, Oxford or Modrrna vaccines etc.

Reply privatelyReply in forumReply +quote
 

By (user no longer on site)
over a year ago


"There’s quite a few alternative technologies out there, which have come and gone, like transdermal injections. For one reason or another they haven’t taken off. "
Swansea University are currently working on a "smart patch"

Reply privatelyReply in forumReply +quote
 

By *inky_couple2020Couple
over a year ago

North West

The problem with new technology is getting people to invest in rolling it out, even if it works. If it's cheaper and easier to keep jabbing people with hypodermics, why spend tons on an alternative that might not, at least at first, be any more effective? That's why it's taken since 1989 to get an mRNA vaccine to market, for example. Finally the world saw the need to speculate, but in the past, despite the technology being there, no investor fancied backing that unknown horse.

Reply privatelyReply in forumReply +quote
 

By (user no longer on site)
over a year ago

I have no problem with needles or vaccinations. But tablets could be a good idea for some, particularly in getting the rest of the world protected where tablets would be much easier to distribute than the vaccine.

Reply privatelyReply in forumReply +quote
 

By *inky_couple2020Couple
over a year ago

North West


"I have no problem with needles or vaccinations. But tablets could be a good idea for some, particularly in getting the rest of the world protected where tablets would be much easier to distribute than the vaccine."

A tablet vaccine is pretty hard to conceive. It'd have to survive the highly acidic pH of the stomach and I'd imagine this is rather challenging for biological material which denatures at such pH. Also the issue of storage for stability etc.

Reply privatelyReply in forumReply +quote
 

By (user no longer on site)
over a year ago


"I have no problem with needles or vaccinations. But tablets could be a good idea for some, particularly in getting the rest of the world protected where tablets would be much easier to distribute than the vaccine.

A tablet vaccine is pretty hard to conceive. It'd have to survive the highly acidic pH of the stomach and I'd imagine this is rather challenging for biological material which denatures at such pH. Also the issue of storage for stability etc. "

I don't know about the technical side of it. Just thinking of distribution, particularly to third world countries.

Reply privatelyReply in forumReply +quote
 

By (user no longer on site)
over a year ago

I'm sure children under 5 get given a flu vaccine in a maisel spray. I'm pretty sure all though I could be wrong even if they have a disability or needle phobia cant have it.

Reply privatelyReply in forumReply +quote
 

By *hrista BellendWoman
over a year ago

surrounded by twinkly lights


"There’s quite a few alternative technologies out there, which have come and gone, like transdermal injections. For one reason or another they haven’t taken off. Swansea University are currently working on a "smart patch""

The nose filters are also being re worked and coating nasal sprays similar to hay-fever sprays

Reply privatelyReply in forumReply +quote
 

By *ophieslut OP   TV/TS
over a year ago

Central

Vaccines in pill form have been under development for some years, with flu and others amongst them. There's a covid vaccine pill under trial at present and others in development. Production, transport and patient delivery are lower cost and easier. Perfect for 3rd world countries, with sparse medical facilities or impossible low temperature storages options of liquid vaccines.

A major problem this year has been production and availability of syringes and needles, which needs are eliminated with pills.

Reply privatelyReply in forumReply +quote
 

By *naswingdressWoman
over a year ago

Manchester (she/her)


"Vaccines in pill form have been under development for some years, with flu and others amongst them. There's a covid vaccine pill under trial at present and others in development. Production, transport and patient delivery are lower cost and easier. Perfect for 3rd world countries, with sparse medical facilities or impossible low temperature storages options of liquid vaccines.

A major problem this year has been production and availability of syringes and needles, which needs are eliminated with pills. "

Yes, I heard a comment about whether a needle shortage might mean a nasal vaccine is needed.

Reply privatelyReply in forumReply +quote
 
 

By *esmond and Molly JonesCouple
over a year ago

Watford

A small prick has never bothered me.

Reply privatelyReply in forumReply +quote
Post new Message to Thread
back to top