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"Yep I'm surprised it's took this long to find a post on it. It's good and bad...good that they are halting it to explore it more. Bad for the poor volunteer who has had a bad reaction. And a setback to us all." Currently checjing to see "if the mystery illness is linked in any way to vaccine" The problem being people can get ill for many reasons. The programme was paused for 10 days in July for same/similar reason.....turned out to have no link at all that time. Lets hope same this time.... | |||
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"Yep I'm surprised it's took this long to find a post on it. It's good and bad...good that they are halting it to explore it more. Bad for the poor volunteer who has had a bad reaction. And a setback to us all. Currently checjing to see "if the mystery illness is linked in any way to vaccine" The problem being people can get ill for many reasons. The programme was paused for 10 days in July for same/similar reason.....turned out to have no link at all that time. Lets hope same this time...." Totally agree | |||
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"It's the second time that they have stopped the trail because a volunteer has become ill. There is no evidence that it is the vaccine that caused it as yet but until all tests on the person are completed they stop the trial. The illness could be anything and has probably nothing to do with the vaccine as was the first case. Don't believe the BBC. " This | |||
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"It's the second time that they have stopped the trail because a volunteer has become ill. There is no evidence that it is the vaccine that caused it as yet but until all tests on the person are completed they stop the trial. The illness could be anything and has probably nothing to do with the vaccine as was the first case. Don't believe the BBC. " The bbc reporter basically said the same as you. So I won’t believe him. | |||
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"Actually it may sound bad... but this is actually perfectly normal standard practice.. and is fairly common If anyone comes out with an adverse reaction not seen in the phase 2 stage... the phase 3 is stopped to make sure it isn’t for example a faulty batch or something that needs further investigation for example if someone was taking another medication for something else that may have triggered this reaction... At the moment this is 1 person in 30000 volunteers... it may be something they have to report on as a very rare side effect but not common enough to stop going forward" Are you saying 30,000 people are on the Oxford trial? Seems unlikely . | |||
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"So has anyone asked about the volunteer? What did they come down with? What component made the reaction so serious?" this is the official statement that has come out this afternoon... "As part of the ongoing randomised, controlled clinical trials of the AstraZeneca Oxford coronavirus vaccine, AZD1222, a standard review process has been triggered, leading to the voluntary pause of vaccination across all trials to allow an independent committee to review the safety data of a single event of an unexplained illness that occurred in the UK Phase III trial. This is a routine action which has to happen whenever there is a potentially unexplained illness in one of the trials, while it is investigated, ensuring we maintain the integrity of the trials. In large clinical trials, illnesses will happen by chance and must be independently reviewed. AstraZeneca is working to expedite the review of the single event to minimise any potential impact on the trial timeline. We are committed to the safety of our participants and the highest standards of conduct in our trials." | |||
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"Actually it may sound bad... but this is actually perfectly normal standard practice.. and is fairly common If anyone comes out with an adverse reaction not seen in the phase 2 stage... the phase 3 is stopped to make sure it isn’t for example a faulty batch or something that needs further investigation for example if someone was taking another medication for something else that may have triggered this reaction... At the moment this is 1 person in 30000 volunteers... it may be something they have to report on as a very rare side effect but not common enough to stop going forward Are you saying 30,000 people are on the Oxford trial? Seems unlikely . " That's in Brazil, South Africa and India as well as health professionals in the UK. | |||
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"So has anyone asked about the volunteer? What did they come down with? What component made the reaction so serious? this is the official statement that has come out this afternoon... "As part of the ongoing randomised, controlled clinical trials of the AstraZeneca Oxford coronavirus vaccine, AZD1222, a standard review process has been triggered, leading to the voluntary pause of vaccination across all trials to allow an independent committee to review the safety data of a single event of an unexplained illness that occurred in the UK Phase III trial. This is a routine action which has to happen whenever there is a potentially unexplained illness in one of the trials, while it is investigated, ensuring we maintain the integrity of the trials. In large clinical trials, illnesses will happen by chance and must be independently reviewed. AstraZeneca is working to expedite the review of the single event to minimise any potential impact on the trial timeline. We are committed to the safety of our participants and the highest standards of conduct in our trials." " Is that the Rebecca Robbins report? | |||
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"The New York Times is reporting a volunteer in the UK trial has been diagnosed with transverse myelitis, an inflammatory syndrome that affects the spinal cord and can be caused by viral infections. Normally a vaccine of this type takes ten years (I'm just quoting an ex Astra Zeneca employee). Scary to try an rush this through. Feel free to get your shots but I won't be doing so nor is there any need as there is around a 99.96% survival rate from catching CV19 for the average person." It's not being rushed through. It's going through the same process as any other vaccination. It's just being put at the front of the queue at each stage of the process. | |||
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"The New York Times is reporting a volunteer in the UK trial has been diagnosed with transverse myelitis, an inflammatory syndrome that affects the spinal cord and can be caused by viral infections. Normally a vaccine of this type takes ten years (I'm just quoting an ex Astra Zeneca employee). Scary to try an rush this through. Feel free to get your shots but I won't be doing so nor is there any need as there is around a 99.96% survival rate from catching CV19 for the average person. It's not being rushed through. It's going through the same process as any other vaccination. It's just being put at the front of the queue at each stage of the process." Now that bit about it being rushed through always gets me. Name any other vaccines that have had the billions of pounds to fund them like this has had...and they might realise how it's going through as fast as possible. The funding has never been there for other vaccines. Hence why they take for ever. Sort of tells all the naysayers the seriousness of this virus. | |||
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"The New York Times is reporting a volunteer in the UK trial has been diagnosed with transverse myelitis, an inflammatory syndrome that affects the spinal cord and can be caused by viral infections. Normally a vaccine of this type takes ten years (I'm just quoting an ex Astra Zeneca employee). Scary to try an rush this through. Feel free to get your shots but I won't be doing so nor is there any need as there is around a 99.96% survival rate from catching CV19 for the average person. It's not being rushed through. It's going through the same process as any other vaccination. It's just being put at the front of the queue at each stage of the process. Now that bit about it being rushed through always gets me. Name any other vaccines that have had the billions of pounds to fund them like this has had...and they might realise how it's going through as fast as possible. The funding has never been there for other vaccines. Hence why they take for ever. Sort of tells all the naysayers the seriousness of this virus. " It is quite apparent that a lot of "facts" that appear on the forum got here straight from a d*unken conversation at the pub without passing "go" or a Google search in between. It seems Hilary Koprowski has a lot to amswer for... | |||
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"Actually it may sound bad... but this is actually perfectly normal standard practice.. and is fairly common If anyone comes out with an adverse reaction not seen in the phase 2 stage... the phase 3 is stopped to make sure it isn’t for example a faulty batch or something that needs further investigation for example if someone was taking another medication for something else that may have triggered this reaction... At the moment this is 1 person in 30000 volunteers... it may be something they have to report on as a very rare side effect but not common enough to stop going forward Are you saying 30,000 people are on the Oxford trial? Seems unlikely . That's in Brazil, South Africa and India as well as health professionals in the UK." Then the relevant percentage is based on the number of people in the Oxford trial receiving a vaccine and not a placebo . Any reference to include other trials of other makes of vaccines is bogus. | |||
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"Actually it may sound bad... but this is actually perfectly normal standard practice.. and is fairly common If anyone comes out with an adverse reaction not seen in the phase 2 stage... the phase 3 is stopped to make sure it isn’t for example a faulty batch or something that needs further investigation for example if someone was taking another medication for something else that may have triggered this reaction... At the moment this is 1 person in 30000 volunteers... it may be something they have to report on as a very rare side effect but not common enough to stop going forward Are you saying 30,000 people are on the Oxford trial? Seems unlikely . That's in Brazil, South Africa and India as well as health professionals in the UK. Then the relevant percentage is based on the number of people in the Oxford trial receiving a vaccine and not a placebo . Any reference to include other trials of other makes of vaccines is bogus. " The Oxford AstraZeneca Chaddox-one vaccine is being trialed in other countries because at the time there weren't enough cases in the UK to make a trial valid. It's actually the UK trials that have less validity. | |||
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"It's the second time that they have stopped the trail because a volunteer has become ill. There is no evidence that it is the vaccine that caused it as yet but until all tests on the person are completed they stop the trial. The illness could be anything and has probably nothing to do with the vaccine as was the first case. Don't believe the BBC. This " Apart from The BBC said exactly the above Trial halted Happend before Normal protocol May or may not have a link with vaccine So which bit should I ignore ??? | |||
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"It's the second time that they have stopped the trail because a volunteer has become ill. There is no evidence that it is the vaccine that caused it as yet but until all tests on the person are completed they stop the trial. The illness could be anything and has probably nothing to do with the vaccine as was the first case. Don't believe the BBC. The bbc reporter basically said the same as you. So I won’t believe him." | |||
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"The New York Times is reporting a volunteer in the UK trial has been diagnosed with transverse myelitis, an inflammatory syndrome that affects the spinal cord and can be caused by viral infections. Normally a vaccine of this type takes ten years (I'm just quoting an ex Astra Zeneca employee). Scary to try an rush this through. Feel free to get your shots but I won't be doing so nor is there any need as there is around a 99.96% survival rate from catching CV19 for the average person. It's not being rushed through. It's going through the same process as any other vaccination. It's just being put at the front of the queue at each stage of the process. Now that bit about it being rushed through always gets me. Name any other vaccines that have had the billions of pounds to fund them like this has had...and they might realise how it's going through as fast as possible. The funding has never been there for other vaccines. Hence why they take for ever. Sort of tells all the naysayers the seriousness of this virus. " Vaccines are being fast-tracked, not 'rushed'. Getting something done faster than usual because it's the overwhelming priority does not imply a lack of care or quality. | |||
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" Vaccines are being fast-tracked, not 'rushed'. Getting something done faster than usual because it's the overwhelming priority does not imply a lack of care or quality. " I suggest that you read Yardley Yeadons response to the vaccine consultation then. He has a degree in Biochemistry & Toxicology & a research based PhD in pharmacology. He spent 32 years working in pharmaceutical R&D, mostly in new medicines for disorders of lung & skin. He was a VP at Pfizer & CEO of a biotech company he founded that was bought by Novartis. As I'm not allowed to post links or cut and paste his response but basically he has massive safety concerns. Look him up on Twitter. | |||
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"The New York Times is reporting a volunteer in the UK trial has been diagnosed with transverse myelitis, an inflammatory syndrome that affects the spinal cord and can be caused by viral infections. Normally a vaccine of this type takes ten years (I'm just quoting an ex Astra Zeneca employee). Scary to try an rush this through. Feel free to get your shots but I won't be doing so nor is there any need as there is around a 99.96% survival rate from catching CV19 for the average person. It's not being rushed through. It's going through the same process as any other vaccination. It's just being put at the front of the queue at each stage of the process. Now that bit about it being rushed through always gets me. Name any other vaccines that have had the billions of pounds to fund them like this has had...and they might realise how it's going through as fast as possible. The funding has never been there for other vaccines. Hence why they take for ever. Sort of tells all the naysayers the seriousness of this virus. It is quite apparent that a lot of "facts" that appear on the forum got here straight from a d*unken conversation at the pub without passing "go" or a Google search in between. It seems Hilary Koprowski has a lot to amswer for..." What gets me is that those who deny it's a deadly virus.....hang about on a virus section | |||
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" Vaccines are being fast-tracked, not 'rushed'. Getting something done faster than usual because it's the overwhelming priority does not imply a lack of care or quality. I suggest that you read Yardley Yeadons response to the vaccine consultation then. He has a degree in Biochemistry & Toxicology & a research based PhD in pharmacology. He spent 32 years working in pharmaceutical R&D, mostly in new medicines for disorders of lung & skin. He was a VP at Pfizer & CEO of a biotech company he founded that was bought by Novartis. As I'm not allowed to post links or cut and paste his response but basically he has massive safety concerns. Look him up on Twitter. " So what are these massive safety concerns? | |||
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"The New York Times is reporting a volunteer in the UK trial has been diagnosed with transverse myelitis, an inflammatory syndrome that affects the spinal cord and can be caused by viral infections. Normally a vaccine of this type takes ten years (I'm just quoting an ex Astra Zeneca employee). Scary to try an rush this through. Feel free to get your shots but I won't be doing so nor is there any need as there is around a 99.96% survival rate from catching CV19 for the average person. It's not being rushed through. It's going through the same process as any other vaccination. It's just being put at the front of the queue at each stage of the process. Now that bit about it being rushed through always gets me. Name any other vaccines that have had the billions of pounds to fund them like this has had...and they might realise how it's going through as fast as possible. The funding has never been there for other vaccines. Hence why they take for ever. Sort of tells all the naysayers the seriousness of this virus. It is quite apparent that a lot of "facts" that appear on the forum got here straight from a d*unken conversation at the pub without passing "go" or a Google search in between. It seems Hilary Koprowski has a lot to amswer for... What gets me is that those who deny it's a deadly virus.....hang about on a virus section " If I could have a penny for every time someone has quoted that more people die from the flu that Covid-19.... In March people were saying it's just a sniffle. In May when there were 500 people a day dying from it the all went quiet. Now they are back again saying it's just a sniffle. In less than a year more than 900 000 people have died from that sniffle. | |||
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" . So what are these massive safety concerns?" That amongst other things no one knows what the safety profile will be in six moths or a year or longer after dosing as there is no data. Also a number of the vaccine being developed utilise novel technology which have not previously been used to create vaccines. There is therefore no long term safety data which can be pointed to in support of the notion that it’s reasonable to expedite development & to waive absent safety information on this occasion. Still what does the ex VP at Pfizer know eh? | |||
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" . So what are these massive safety concerns? That amongst other things no one knows what the safety profile will be in six moths or a year or longer after dosing as there is no data. Also a number of the vaccine being developed utilise novel technology which have not previously been used to create vaccines. There is therefore no long term safety data which can be pointed to in support of the notion that it’s reasonable to expedite development & to waive absent safety information on this occasion. Still what does the ex VP at Pfizer know eh?" Ex's never have a good word to say | |||
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"It's the second time that they have stopped the trail because a volunteer has become ill. There is no evidence that it is the vaccine that caused it as yet but until all tests on the person are completed they stop the trial. The illness could be anything and has probably nothing to do with the vaccine as was the first case. Don't believe the BBC. This " I must clarify, I intended to support the explanation of the poster of this information. I wouldn't personally say "don't believe the BBC", although one had to read all of the article on BBC news app this morning to get the full picture. Anyone who read the attention grabbing headline on its own may have been led to believe the trial being halted was more significant than a routine thing due to an unexplained medical event, which may or may not be linked to the trial. | |||
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" If I could have a penny for every time someone has quoted that more people die from the flu that Covid-19.... " I'd hold out for a pound for every time someone talks about getting run over by a bus... | |||
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" . So what are these massive safety concerns? That amongst other things no one knows what the safety profile will be in six moths or a year or longer after dosing as there is no data. Also a number of the vaccine being developed utilise novel technology which have not previously been used to create vaccines. There is therefore no long term safety data which can be pointed to in support of the notion that it’s reasonable to expedite development & to waive absent safety information on this occasion. Still what does the ex VP at Pfizer know eh?" Ok so you've listed some less than ideal conditions. Yes we don't have long term data. It would be nice to have that info. Are these the massive safety concerns you were referring to? Whilst the person raising the concerns may be well qualified, I would hazard a guess that the people producing this vaccine aren't exactly hobbyists either. Same for those reglating the legislative approval. | |||
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"It's a good sign that's showing how thoroughly they are taking safety concerns, as they would always do with other vaccines. Hoping it's not anything significant, nor anything more than a short pause. " | |||
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" Vaccines are being fast-tracked, not 'rushed'. Getting something done faster than usual because it's the overwhelming priority does not imply a lack of care or quality. I suggest that you read Yardley Yeadons response to the vaccine consultation then. He has a degree in Biochemistry & Toxicology & a research based PhD in pharmacology. He spent 32 years working in pharmaceutical R&D, mostly in new medicines for disorders of lung & skin. He was a VP at Pfizer & CEO of a biotech company he founded that was bought by Novartis. As I'm not allowed to post links or cut and paste his response but basically he has massive safety concerns. Look him up on Twitter. " Nah, I'm fine thanks. You could have cut and pasted the key points if you wanted to. It's very telling when people are just 'this person agrees with me!' without providing any of the actual context. | |||
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" . So what are these massive safety concerns? That amongst other things no one knows what the safety profile will be in six moths or a year or longer after dosing as there is no data. Also a number of the vaccine being developed utilise novel technology which have not previously been used to create vaccines. There is therefore no long term safety data which can be pointed to in support of the notion that it’s reasonable to expedite development & to waive absent safety information on this occasion. Still what does the ex VP at Pfizer know eh? Ex's never have a good word to say " Ahh. A note of levity! I do wish people here wouldn't get so wound up and aggressive. I'm sure most original posters only do it to pass on information. Unfortunately so many people believe what is now termed false news so jump on any slightly controversial topic. I'm the old fashioned type and still think the BBC is probably the best and most reliable source rather than many of the others?( ducks head down to avoid brickbats!) | |||
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"Government right now are going to change law once a consultation has been consulted. The government want to push unlicensed vaccines to be made mandatory. There is information about this on government Web page " Care to provide a link. Because not seen anything about this anywhere. | |||
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"Government right now are going to change law once a consultation has been consulted. The government want to push unlicensed vaccines to be made mandatory. There is information about this on government Web page Care to provide a link. Because not seen anything about this anywhere." It's on gov.uk in between where the government plans to harvest our organs and sell them to Donald Trump, and where they reveal plans to enslave us to work on alien planets. Gotta love transparency. | |||
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"Government right now are going to change law once a consultation has been consulted. The government want to push unlicensed vaccines to be made mandatory. There is information about this on government Web page Care to provide a link. Because not seen anything about this anywhere. It's on gov.uk in between where the government plans to harvest our organs and sell them to Donald Trump, and where they reveal plans to enslave us to work on alien planets. Gotta love transparency. " Be the same bill which mandates we have already compulsory voted Tory for the next election.. Dave a fortune by not having a campaign.. | |||
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"Government right now are going to change law once a consultation has been consulted. The government want to push unlicensed vaccines to be made mandatory. There is information about this on government Web page Care to provide a link. Because not seen anything about this anywhere. It's on gov.uk in between where the government plans to harvest our organs and sell them to Donald Trump, and where they reveal plans to enslave us to work on alien planets. Gotta love transparency. Be the same bill which mandates we have already compulsory voted Tory for the next election.. Dave a fortune by not having a campaign.." So different process, same result? | |||
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"It was because someone got nerve damage from it." Has it been proven that the vaccine was the cause? | |||
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"It was because someone got nerve damage from it. Has it been proven that the vaccine was the cause?" If it's not referenced, I'd take it as like hearsay, as an investigation to be thorough enough to get the trial restarted and for the final research evidence report, would need to be absolutely watertight. To issue confidential information about a volunteer would also be somewhat remiss and unethical. | |||
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"It was because someone got nerve damage from it. Has it been proven that the vaccine was the cause?" It hasn't. Every modern successful vaccine development has had more than one pause in it. | |||
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"It was because someone got nerve damage from it. Has it been proven that the vaccine was the cause?" They are investigating it but they did say it could of been it, it was on sky news yesterday, they explained that it also is a "rush vaccine" a vaccine normally takes years sometimes 10 years to develop. | |||
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"It was because someone got nerve damage from it. Has it been proven that the vaccine was the cause?They are investigating it but they did say it could of been it, it was on sky news yesterday, they explained that it also is a "rush vaccine" a vaccine normally takes years sometimes 10 years to develop." Also they didnt know what the side effects could be by using it. | |||
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"It was because someone got nerve damage from it. Has it been proven that the vaccine was the cause?They are investigating it but they did say it could of been it, it was on sky news yesterday, they explained that it also is a "rush vaccine" a vaccine normally takes years sometimes 10 years to develop." Rush is probably a bad term. It has gone through, and is still going through, every step that any other vaccination does, except that this vaccine is being put at the front of every queue. | |||
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"It was because someone got nerve damage from it. Has it been proven that the vaccine was the cause?They are investigating it but they did say it could of been it, it was on sky news yesterday, they explained that it also is a "rush vaccine" a vaccine normally takes years sometimes 10 years to develop. Rush is probably a bad term. It has gone through, and is still going through, every step that any other vaccination does, except that this vaccine is being put at the front of every queue. " Yes it might mean that, we will see what the outcome of the investigation will be. | |||
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"It was because someone got nerve damage from it. Has it been proven that the vaccine was the cause?They are investigating it but they did say it could of been it, it was on sky news yesterday, they explained that it also is a "rush vaccine" a vaccine normally takes years sometimes 10 years to develop. Rush is probably a bad term. It has gone through, and is still going through, every step that any other vaccination does, except that this vaccine is being put at the front of every queue. Yes it might mean that, we will see what the outcome of the investigation will be." Fingers crossed | |||
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"It was because someone got nerve damage from it. Has it been proven that the vaccine was the cause?They are investigating it but they did say it could of been it, it was on sky news yesterday, they explained that it also is a "rush vaccine" a vaccine normally takes years sometimes 10 years to develop. Rush is probably a bad term. It has gone through, and is still going through, every step that any other vaccination does, except that this vaccine is being put at the front of every queue. Yes it might mean that, we will see what the outcome of the investigation will be. Fingers crossed " Yes, fingers crossed for it too | |||
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"Vaccine trial restarted again. Is it just in uk?" The stage 3 trials are taking place in countries around the world. More info: https://www.bbc.co.uk/news/uk-54132066 | |||
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"Vaccine trial restarted again." "AstraZeneca said it received confirmation from the United Kingdom's Medicines Health Regulatory Authority that it was safe to resume clinical trials" | |||
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