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Herd immunity

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By *ylonSlut OP   TV/TS
over a year ago

Durham

Interesting reading about the kings college report about antibodies and immunity. Basically the number of antibodies people have after being infected drops to virtually nil after 2 or 3 months in most people. This would make achieving natural herd immunity virtually impossible in a short timeframe. In another part of the study, done on monkeys i may add, the vaccine they were working on doesn't produce as high a antibody response as a typical covid infection. The bad news is that vaccinated monkeys could get infected again after a while and pass on covid to others. The good news is that the monkeys seem to have enough antibodies not to get really sick. Not amazing but a vaccine with booster shots would we could return to a normal way of life sooner.

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By *limmatureguyMan
over a year ago

Tonbridge


"Interesting reading about the kings college report about antibodies and immunity. Basically the number of antibodies people have after being infected drops to virtually nil after 2 or 3 months in most people. This would make achieving natural herd immunity virtually impossible in a short timeframe. In another part of the study, done on monkeys i may add, the vaccine they were working on doesn't produce as high a antibody response as a typical covid infection. The bad news is that vaccinated monkeys could get infected again after a while and pass on covid to others. The good news is that the monkeys seem to have enough antibodies not to get really sick. Not amazing but a vaccine with booster shots would we could return to a normal way of life sooner."

That said, after four months, no-one has caught twice, so maybe it's the T cells that are protecting people.

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By *ylonSlut OP   TV/TS
over a year ago

Durham


"Interesting reading about the kings college report about antibodies and immunity. Basically the number of antibodies people have after being infected drops to virtually nil after 2 or 3 months in most people. This would make achieving natural herd immunity virtually impossible in a short timeframe. In another part of the study, done on monkeys i may add, the vaccine they were working on doesn't produce as high a antibody response as a typical covid infection. The bad news is that vaccinated monkeys could get infected again after a while and pass on covid to others. The good news is that the monkeys seem to have enough antibodies not to get really sick. Not amazing but a vaccine with booster shots would we could return to a normal way of life sooner.

That said, after four months, no-one has caught twice, so maybe it's the T cells that are protecting people."

But its the infection or vaccine that provoke production of the t cells? The study has said monkeys can catch it twice but don't get very sick twice. They can still pass it on.

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By *ophieslutTV/TS
over a year ago

Central

It's still very early days in our gaining an understanding of the virus. Any vaccines would need to be delivered in a programme that would develop meaningful resistance. That may be via multiple treatments and could be supported from herd immunity achieved from vaccinations, so it can't take hold as few can catch it and pass it on.

It's a pity that there are people who are against having any of the vaccines that may be produced for this, as they could become the weak achilles heal, so that we continue to suffer beyond when we could be free from this.

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By *iewMan
Forum Mod

over a year ago

Angus & Findhorn

Please do not post links that are not allowed on the thread, I have included the rules for reference:

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You can link to:

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By (user no longer on site)
over a year ago


"Interesting reading about the kings college report about antibodies and immunity. Basically the number of antibodies people have after being infected drops to virtually nil after 2 or 3 months in most people. This would make achieving natural herd immunity virtually impossible in a short timeframe. In another part of the study, done on monkeys i may add, the vaccine they were working on doesn't produce as high a antibody response as a typical covid infection. The bad news is that vaccinated monkeys could get infected again after a while and pass on covid to others. The good news is that the monkeys seem to have enough antibodies not to get really sick. Not amazing but a vaccine with booster shots would we could return to a normal way of life sooner.

That said, after four months, no-one has caught twice, so maybe it's the T cells that are protecting people."

There’s been a number of cases of those suffering ‘relapsing’ with the infection. There’s a lack of knowledge over whether that is being re-infected or never fully recovering and then the virus symptoms returning.

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By *ust RachelTV/TS
over a year ago

Horsham


"Interesting reading about the kings college report about antibodies and immunity. Basically the number of antibodies people have after being infected drops to virtually nil after 2 or 3 months in most people. This would make achieving natural herd immunity virtually impossible in a short timeframe. In another part of the study, done on monkeys i may add, the vaccine they were working on doesn't produce as high a antibody response as a typical covid infection. The bad news is that vaccinated monkeys could get infected again after a while and pass on covid to others. The good news is that the monkeys seem to have enough antibodies not to get really sick. Not amazing but a vaccine with booster shots would we could return to a normal way of life sooner.

That said, after four months, no-one has caught twice, so maybe it's the T cells that are protecting people."

They reckon someone has caught it twice, but they are being checked carefully to ensure it is not a reinfection

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By (user no longer on site)
over a year ago


"Interesting reading about the kings college report about antibodies and immunity. Basically the number of antibodies people have after being infected drops to virtually nil after 2 or 3 months in most people. This would make achieving natural herd immunity virtually impossible in a short timeframe. In another part of the study, done on monkeys i may add, the vaccine they were working on doesn't produce as high a antibody response as a typical covid infection. The bad news is that vaccinated monkeys could get infected again after a while and pass on covid to others. The good news is that the monkeys seem to have enough antibodies not to get really sick. Not amazing but a vaccine with booster shots would we could return to a normal way of life sooner.

That said, after four months, no-one has caught twice, so maybe it's the T cells that are protecting people.

There’s been a number of cases of those suffering ‘relapsing’ with the infection. There’s a lack of knowledge over whether that is being re-infected or never fully recovering and then the virus symptoms returning.

"

I seen a bit of that earlier on the news...it seems a bugger for months after catching it with it interfering with the circulation system...some getting blood clot further down the line. It's a nasty bugger alright...

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By (user no longer on site)
over a year ago

Think people need to stop thinking there will be a cure. At best it will be like the flu jab, it won't necessarily stop you getting it but will make it less deadly.

The fact that the antibodies do not stay long isn't a surprise, this is the same with a lot of respiratory illnesses.

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By *V-AliceTV/TS
over a year ago

Ayr


"Think people need to stop thinking there will be a cure. At best it will be like the flu jab, it won't necessarily stop you getting it but will make it less deadly.

The fact that the antibodies do not stay long isn't a surprise, this is the same with a lot of respiratory illnesses."

Exactly.

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By *D835Man
over a year ago

London


"Interesting reading about the kings college report about antibodies and immunity. Basically the number of antibodies people have after being infected drops to virtually nil after 2 or 3 months in most people. This would make achieving natural herd immunity virtually impossible in a short timeframe. In another part of the study, done on monkeys i may add, the vaccine they were working on doesn't produce as high a antibody response as a typical covid infection. The bad news is that vaccinated monkeys could get infected again after a while and pass on covid to others. The good news is that the monkeys seem to have enough antibodies not to get really sick. Not amazing but a vaccine with booster shots would we could return to a normal way of life sooner.

That said, after four months, no-one has caught twice, so maybe it's the T cells that are protecting people."

“.... so maybe it's the T cells that are protecting people....”

T cells don’t prevent you from catching the virus. What T cells do, is destroy already infected cells.

T cells don’t prevent reinfection, nor do they prevent an infected person from transmitting the virus.

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By (user no longer on site)
over a year ago

US military found that flu vaccine was causing viral interference and increasing risk of Covid. Wonder if the reverse will be true. Will you be able to have both or will they react to each other?

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By (user no longer on site)
over a year ago

Have we given up on herd immunity in UK? Seems that we're trying to contain it now when previously it was all about 'flattening' the curve.

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By *iddle ManMan
over a year ago

Walsall

The way it is going, with no workable mass vaccine coming then we might be looking at this virus being part of everyday life for the foreseeable future. If the antibody theory is true then it will circulate around, hopefully in time enough people will have the antibodies to just fight it off much like other virus and have mild to no symptoms. Problem being there will be some that will either not had it or can't fight it off.

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By (user no longer on site)
over a year ago


"Interesting reading about the kings college report about antibodies and immunity. Basically the number of antibodies people have after being infected drops to virtually nil after 2 or 3 months in most people. This would make achieving natural herd immunity virtually impossible in a short timeframe. In another part of the study, done on monkeys i may add, the vaccine they were working on doesn't produce as high a antibody response as a typical covid infection. The bad news is that vaccinated monkeys could get infected again after a while and pass on covid to others. The good news is that the monkeys seem to have enough antibodies not to get really sick. Not amazing but a vaccine with booster shots would we could return to a normal way of life sooner.

That said, after four months, no-one has caught twice, so maybe it's the T cells that are protecting people.

There’s been a number of cases of those suffering ‘relapsing’ with the infection. There’s a lack of knowledge over whether that is being re-infected or never fully recovering and then the virus symptoms returning.

I seen a bit of that earlier on the news...it seems a bugger for months after catching it with it interfering with the circulation system...some getting blood clot further down the line. It's a nasty bugger alright..."

We’ve had a couple of patients swabbed clear during recovery, been discharged and then had them re-admitted positive a few weeks later.

As for recovery... yup for some people it’s a very long haul back. For some sadly they can be clear of the virus but sadly not recover from the damage the body has sustained.

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By (user no longer on site)
over a year ago


"Have we given up on herd immunity in UK? Seems that we're trying to contain it now when previously it was all about 'flattening' the curve."

There’s growing evidence that immunity is usually gone within 3 months. The antibody testing has been thought to have a 20% inaccuracy in results but timelines now seem to be suggesting that perhaps it’s confirming what lab testing is currently showing... immunity is pretty short lived.

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By *limmatureguyMan
over a year ago

Tonbridge


"

We’ve had a couple of patients swabbed clear during recovery, been discharged and then had them re-admitted positive a few weeks."

Research was done on this situation of a second positive test by the Korea Centre for disease control and it was found that the test was detecting dead virus particles and no evidence of live virus was found in the patients. The test is very good at detecting traces of the virus, it doesn't show whether the patient is infectious.

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By *ylonSlut OP   TV/TS
over a year ago

Durham


"

We’ve had a couple of patients swabbed clear during recovery, been discharged and then had them re-admitted positive a few weeks.

Research was done on this situation of a second positive test by the Korea Centre for disease control and it was found that the test was detecting dead virus particles and no evidence of live virus was found in the patients. The test is very good at detecting traces of the virus, it doesn't show whether the patient is infectious."

Not heard that pcr test amplify dna and i would thought the test would differentiate between a live and dead virus, but stand to be corrected. The study with macaques found they could be reinfected and could be come infectious. There is hearsay evidence it happens in humans too but no solid evidence.

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By (user no longer on site)
over a year ago


"

We’ve had a couple of patients swabbed clear during recovery, been discharged and then had them re-admitted positive a few weeks.

Research was done on this situation of a second positive test by the Korea Centre for disease control and it was found that the test was detecting dead virus particles and no evidence of live virus was found in the patients. The test is very good at detecting traces of the virus, it doesn't show whether the patient is infectious."

As both our patients went back onto oxygen and deteriorated I think it’s safe to say the virus was very much still active for them x

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By *limmatureguyMan
over a year ago

Tonbridge


"

We’ve had a couple of patients swabbed clear during recovery, been discharged and then had them re-admitted positive a few weeks.

Research was done on this situation of a second positive test by the Korea Centre for disease control and it was found that the test was detecting dead virus particles and no evidence of live virus was found in the patients. The test is very good at detecting traces of the virus, it doesn't show whether the patient is infectious.

Not heard that pcr test amplify dna and i would thought the test would differentiate between a live and dead virus, but stand to be corrected. The study with macaques found they could be reinfected and could be come infectious. There is hearsay evidence it happens in humans too but no solid evidence. "

If you search 'Tests in recovered patients found false positives' you can see the study. The PCR test cannot tell the difference between RNA from a dead or live viruses.

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By *limmatureguyMan
over a year ago

Tonbridge


"

We’ve had a couple of patients swabbed clear during recovery, been discharged and then had them re-admitted positive a few weeks.

Research was done on this situation of a second positive test by the Korea Centre for disease control and it was found that the test was detecting dead virus particles and no evidence of live virus was found in the patients. The test is very good at detecting traces of the virus, it doesn't show whether the patient is infectious.

As both our patients went back onto oxygen and deteriorated I think it’s safe to say the virus was very much still active for them x"

Did they test negative when they were discharged, or were they just feeling better?

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By *ylonSlut OP   TV/TS
over a year ago

Durham


"

We’ve had a couple of patients swabbed clear during recovery, been discharged and then had them re-admitted positive a few weeks.

Research was done on this situation of a second positive test by the Korea Centre for disease control and it was found that the test was detecting dead virus particles and no evidence of live virus was found in the patients. The test is very good at detecting traces of the virus, it doesn't show whether the patient is infectious.

Not heard that pcr test amplify dna and i would thought the test would differentiate between a live and dead virus, but stand to be corrected. The study with macaques found they could be reinfected and could be come infectious. There is hearsay evidence it happens in humans too but no solid evidence.

If you search 'Tests in recovered patients found false positives' you can see the study. The PCR test cannot tell the difference between RNA from a dead or live viruses. "

It much likely to be a false negative test than a false positive. It is very unlikely, but not quite impossible, that someone would have have dead virus rna in their respiratory tract without live virus being there too. With regards to people getting ill twice what we don't know is it people getting infected twice or is it just the original infection being reactivated after lying dormant for a while.

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By (user no longer on site)
over a year ago


"Please do not post links that are not allowed on the thread, I have included the rules for reference:

Links to other sites

We have restrictions on where you can link to because otherwise people end up posting spam or links to places that host malware/spyware and it's bad for our users.

You can link to:

Any well recognised news site (bbc, times, telegraph, sun, cnn and all the rest)

Youtube

Lovehoney

Wikipedia

Many thanks "

Oh it’s good to see you’re a mod now View

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By *limmatureguyMan
over a year ago

Tonbridge


"

We’ve had a couple of patients swabbed clear during recovery, been discharged and then had them re-admitted positive a few weeks.

Research was done on this situation of a second positive test by the Korea Centre for disease control and it was found that the test was detecting dead virus particles and no evidence of live virus was found in the patients. The test is very good at detecting traces of the virus, it doesn't show whether the patient is infectious.

Not heard that pcr test amplify dna and i would thought the test would differentiate between a live and dead virus, but stand to be corrected. The study with macaques found they could be reinfected and could be come infectious. There is hearsay evidence it happens in humans too but no solid evidence.

If you search 'Tests in recovered patients found false positives' you can see the study. The PCR test cannot tell the difference between RNA from a dead or live viruses.

It much likely to be a false negative test than a false positive. It is very unlikely, but not quite impossible, that someone would have have dead virus rna in their respiratory tract without live virus being there too. With regards to people getting ill twice what we don't know is it people getting infected twice or is it just the original infection being reactivated after lying dormant for a while.

"

If you read the research you will see that's exactly what they found, a pcr test detecting the virus particles but they were not able to grow any live virus from it.

To quote the article 'The respiratory epithelial cell has a half-life of up to three months, and RNA virus in the cell can be detected with PCR testing one to two months after the elimination of the cell,'

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By *ylonSlut OP   TV/TS
over a year ago

Durham


"

We’ve had a couple of patients swabbed clear during recovery, been discharged and then had them re-admitted positive a few weeks.

Research was done on this situation of a second positive test by the Korea Centre for disease control and it was found that the test was detecting dead virus particles and no evidence of live virus was found in the patients. The test is very good at detecting traces of the virus, it doesn't show whether the patient is infectious.

Not heard that pcr test amplify dna and i would thought the test would differentiate between a live and dead virus, but stand to be corrected. The study with macaques found they could be reinfected and could be come infectious. There is hearsay evidence it happens in humans too but no solid evidence.

If you search 'Tests in recovered patients found false positives' you can see the study. The PCR test cannot tell the difference between RNA from a dead or live viruses.

It much likely to be a false negative test than a false positive. It is very unlikely, but not quite impossible, that someone would have have dead virus rna in their respiratory tract without live virus being there too. With regards to people getting ill twice what we don't know is it people getting infected twice or is it just the original infection being reactivated after lying dormant for a while.

If you read the research you will see that's exactly what they found, a pcr test detecting the virus particles but they were not able to grow any live virus from it.

To quote the article 'The respiratory epithelial cell has a half-life of up to three months, and RNA virus in the cell can be detected with PCR testing one to two months after the elimination of the cell,'"

You are right had a good read around. Lots of reasons for a false positive or negative on a PCR. In ideal conditions the PCR test should result in only 10% false negatives and less than 1% false positive. However in the real world an individual test is at best 70% accurate. Sampling, sample storage and sample handling can all bring in errors. For example over time DNA/RNA can break down in a sample to show a false negative.

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By (user no longer on site)
over a year ago


"Please do not post links that are not allowed on the thread, I have included the rules for reference:

Links to other sites

We have restrictions on where you can link to because otherwise people end up posting spam or links to places that host malware/spyware and it's bad for our users.

You can link to:

Any well recognised news site (bbc, times, telegraph, sun, cnn and all the rest)

Youtube

Lovehoney

Wikipedia

Many thanks

Oh it’s good to see you’re a mod now View "

And lovely to have him back contributing.

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By (user no longer on site)
over a year ago


"Please do not post links that are not allowed on the thread, I have included the rules for reference:

Links to other sites

We have restrictions on where you can link to because otherwise people end up posting spam or links to places that host malware/spyware and it's bad for our users.

You can link to:

Any well recognised news site (bbc, times, telegraph, sun, cnn and all the rest)

Youtube

Lovehoney

Wikipedia

Many thanks

Oh it’s good to see you’re a mod now View

And lovely to have him back contributing. "

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