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Methotrexate for psoriasis

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By *rcticstar OP   Woman
over a year ago

Corsham

Hi guys. Was wondering if anyone has taken or is taking methotrexate to treat psoriasis and if they've noticed a difference in the psoriasis. Be greatful for any information anyone can give me as I'm just waiting to go have my bloods done before I start.

Thanks x

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By *ce WingerMan
over a year ago

P.O. Box DE1 0NQ

Have recently been diagnosed with psoriatic arthritis and am off to see the specialist again tomorrow, so would be interested in any responses myself.

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By *rcticstar OP   Woman
over a year ago

Corsham

Do you have the patches with that Hun? 60% of me has patches and its so itchy and unsightly. Let me know how you get on x

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By *ce WingerMan
over a year ago

P.O. Box DE1 0NQ

When I first developed psoriasis in 1988, I was given coaltar cream, but it didn't seem to have much effect and have not really bothered with anything else since.

With the recent diagnosis I have been taking colchicine when I have flare ups. Unfortunately that doesn't work as well as I'd hoped

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By *uby0000Woman
over a year ago

hertfordshire

my brother has been doing a trial injection which has done wonders for him

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By *PLNORTHERNCouple
over a year ago

wakefield

i suddenly got the condition around the age of 18 with a massive flair up from nowhere wit no family history of skin conditions. creams all useless do nothing. puva works great but as soon as i stopped it came back. im now on medication similar and it works a real treat i am almost clear!!! and have been for a few years now!!!!

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By *rcticstar OP   Woman
over a year ago

Corsham

Thanks guys. I first started getting it in 1997. Was going through messy divorce lost my job and lost my baby. It just stayed a little patch on my elbows and knees then in 2007 I developed it on my legs and my arms got worse and got it on my face after problems with new partner so I know stress makes it worse. I've had various creams and ointments and 2 courses of UVB. Nothing has worked so fingers crossed this will work aswell as it has on you guys. Here's hoping! Lol. I now have it on 60% of my body. I just want to wear a dress! X

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By *rcticstar OP   Woman
over a year ago

Corsham

Oh. And the only thing that's actually made a difference is argan oil. Fantastic stuff! X

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By *etentMan
over a year ago

maidstone

Ive been using dovobet ointment for years which keeps it manageable but the only time ive been clear is with PUVA treatment but comes back quickly when i stop...the injections sound interesting..how they go about getting them?

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By (user no longer on site)
over a year ago

My ex wife has it and the arthritis to boot, she is on the injectable stuff now and it does work well, she also takes something called humiea as well which keeps it under control. Hope it works just as well for you if you ever need to chat just message me xx

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By *adyGardenWoman
over a year ago

LONDON (se)

My mum has it on her elbows and knees. I told her to try an emollient cream and it worked for her. I get it very mildly too so just keep exfoliating and putting emollient on which works to keep mine at bay.

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By *rcticstar OP   Woman
over a year ago

Corsham

I've tried betnovate, dovenex, eumavate, exorex, cetreban and diprobase and still no improvement. I'm tired of going back to the doctor and dermatologist lol. I had a better tan having UVB treatment than my sister did who'd gone to Greece! Lol. And on the nhs too lol.

I do find exfoliating then using argan oil tons better than all the above crap lol. But still it's getting worse x

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By (user no longer on site)
over a year ago

3 months in Australia worked for me but it did come back after a while.

Anyone tried Epaderm seems to work quick too but like all the rest when you stop using it it returns. (sometimes)

Feel for you all xx

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By (user no longer on site)
over a year ago

Friend was on methatrexate for rheumatoid arthritis gave her cancer x

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By *ce WingerMan
over a year ago

P.O. Box DE1 0NQ

Cancer of what

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By (user no longer on site)
over a year ago

Cervical it's a side effect

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By (user no longer on site)
over a year ago

my sister has been taking 10mg of methotrexate since febuary. she has had coverage of over 70% which is much worse in the winter months. The Psysoris has all but cleared. she has recently been diagnosed with rheumatoid arthritis but the methotrexate does not appear to be helping that condition at all. She told me that she has started getting sports massages once a month and its helping her move a lot more freely. if you dont plan to have more children it is worth considering as i know my sister has been plagued for years and for the first time in 20 years she went out for a night out without tights. She knows that she will be on the drug for life but its price thats worth paying i hope that you can get relief too. Best wishes

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By *ce WingerMan
over a year ago

P.O. Box DE1 0NQ


"Cervical it's a side effect"

Crikey, I know I don't have a cervix, but I'd sooner have psoriasis than cancer. Like lots of sufferers spend all day in the sun or go under sun beds, surely they are increasing the risk of skin cancer?

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By *orneyashell87Couple
over a year ago

stockotn on tees

I was given it on a drop wen I had an eptopic pregnancy. Terrible stuff n I would advice u seriously think about it before going a head. Try light treatment I know we have that available in our hospital xx

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By *affy55Man
over a year ago

Abergele

I've had psoriasis since the age of 5, and remember going to school with a shaved (kojak style) head for about a year, along with all the coal tar baths, creams etc - nothing worked.

I started nursing in 1972 and around 1975 started using sunbeds

yes, I know also supposed to be unhealthy

as for me: I still use sunbeds 6 mins once a week and I haven't had a patch in about 15 years.

We are all different and sunbeds work for me

BUT

please seek Dr's advice before using them

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By *affy55Man
over a year ago

Abergele

[Removed by poster at 01/10/14 06:42:26]

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By (user no longer on site)
over a year ago

Methotrexate (or MTX as I will refer to it) is an immunosupressant. Once you start on it, you should have bloods done monthly before each repeat prescription. They have to measure the effect on about 10 different markers in your blood (from Vit D to T4-White Cell) in order to ensure the dosage is suppressing your immune system to a normal level.

They have some unpleasant side effects the day after you take your dose (typically MTX is a weekly dose).

One thing I have read about for Psoriasis which can be very beneficial is a high-dose Vitamin D supplement. Not the sort you get in a multivitamin, but a Vit D tablet. There are some made by a company called Vitashine. You can get them off Amazon or direct from the company. They have 1000IU and 2500IU doses available if I recall.

One other thing, if you do try the Vitamin D tablets, be sure to discuss this with your Psoriais consultant when before you take them to ensure they will not interfere with the MTX - they shouldn't, in fact often a Vit D may be needed as MTX can inhibit Vit D uptake.

(My partner has RA and takes MTX and Hydroxychloroquine, hence my layman's knowledge.)

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By *rcticstar OP   Woman
over a year ago

Corsham

Twice I've had UVB treatment at hospital. Went 3 times a week for 3 months and only made a real difference to face and arms as smaller plaques but the legs were so much harder. Soon came back. Great tan though! Lol. I've been told its a drug used to treat cancer but in higher doses and I need bloods done first before I start treatment and weekly to start with then monthly.

Thankyou all for your input. Most informative. Thanks x

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By (user no longer on site)
over a year ago

My dad has been on it for about 13 years for arthritic issues. He has no immune system any more. Smallest cold knocks him for 6. He is the only one who can handle it as it is toxic

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By (user no longer on site)
over a year ago

This has been great to read, there are a few things I haven't tried. I've had it since I was 12, started with a plaque on my scalp and now I've pretty much got it everywhere. My doctor still won't send me to a dermatologist, and I have such a list of lotions and potions that I need a bag to leave the pharmacy!!

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By (user no longer on site)
over a year ago

Our son has arthritis. They started him on it last year.

Was in hospital with severe infection a few weeks later.

He has stopped it now.

The downsides of taking it for him far outweighs the plus as it made little difference to his condition.

Good diet,healthy lifestyle and exercise helps him more.

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By (user no longer on site)
over a year ago


"This has been great to read, there are a few things I haven't tried. I've had it since I was 12, started with a plaque on my scalp and now I've pretty much got it everywhere. My doctor still won't send me to a dermatologist, and I have such a list of lotions and potions that I need a bag to leave the pharmacy!! "

Oatmeal and wheatgerm great for calming scalp.

Porridge oats put through muslin or tights in bath.

They gave me loads of creams and bath additives for my son . Didnt work so i went for natural solutions.

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By (user no longer on site)
over a year ago

I had to take them but had give it up a horible drug withs lots off side affects.

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By (user no longer on site)
over a year ago

I got it on my scalp a few years back.

It's not too bad.

Mainly gets bad when I'm stressed.

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By (user no longer on site)
over a year ago

I was on methotrexate for just over two years I had to go in for blood tests every month to makesure it wasn't damaging my liver and kidneys....... It bring down all your immunity to all diseases had to go for flu jabs, it ages the skin coz it slows down cell production. It relieved the arthritis side also..... I came off it coz I got scared tbh of having no immunity etc

You have to think long and hard and weigh up your options before using it I was chronic sufferer it helps and my skin hasn't been too bad since I stopped.

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By (user no longer on site)
over a year ago

Everyone has different things that helps relieve their symptoms it's a trial an error thing unfortunately ...... Methotrexate is quite often given to ppl with cancer to bring down immunity so that chemo can work quicker an attack the cancerous cells it's a complicated drug

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By (user no longer on site)
over a year ago

Thank you I know Lush has an oatmeal moisturiser I am trying just now. I really need to get back into my yoga, learn to de-stress better!

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By (user no longer on site)
over a year ago


"Methotrexate (or MTX as I will refer to it) is an immunosupressant. Once you start on it, you should have bloods done monthly before each repeat prescription. They have to measure the effect on about 10 different markers in your blood (from Vit D to T4-White Cell) in order to ensure the dosage is suppressing your immune system to a normal level.

They have some unpleasant side effects the day after you take your dose (typically MTX is a weekly dose).

One thing I have read about for Psoriasis which can be very beneficial is a high-dose Vitamin D supplement. Not the sort you get in a multivitamin, but a Vit D tablet. There are some made by a company called Vitashine. You can get them off Amazon or direct from the company. They have 1000IU and 2500IU doses available if I recall.

One other thing, if you do try the Vitamin D tablets, be sure to discuss this with your Psoriais consultant when before you take them to ensure they will not interfere with the MTX - they shouldn't, in fact often a Vit D may be needed as MTX can inhibit Vit D uptake.

(My partner has RA and takes MTX and Hydroxychloroquine, hence my layman's knowledge.) "
agree!! Also if

The sun is out get your kit off & enjoy, works for me x

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